产品货号:
Z28762
中文名称:
TNFRSF5/CD40抗体
英文名称:
Anti-TNFRSF5/CD40 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TNFRSF5/CD40 Antibody |
指标别名 | B cell surface antigen CD40;Bp50;CD40;CD40L receptor;CDW40;p50;TNFRSF5 |
克隆性 | Polyclonal |
检验物种 | mouse,rat |
应用范围 | WB,ELISA |
基因名称 | CD40 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived rat CD40 recombinant protein (Position:V24-R193). |
实际分子量 | 30KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | This CD40 gene is a member of the TNF-receptor superfamily.The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching,memory B cell development,and germinal center formation.AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand,which may be important for homotypic cell interactions.Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction.The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation,and thus is thought to be an early event in Alzheimer disease pathogenesis.Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3).Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Uniprot ID | Q4QQW2 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
推荐稀释比 | Western blot(WB) 1:500~2000 (ELISA): 1:100~1000 |
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